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Registration

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NETWORKING (BREAKFAST provided)

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Welcome Remarks, Introductions & CDMI Update

Drs. Jeffrey Lotz & Vijay Goel – CDMI Site Directors

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Keynote - Bringing AI to the Bedside
Rachael Callcut, MD, MSPH, Associate Professor

Department of Surgery, UC San Francisco

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Introduction to Presentations

Drs. Jeffrey Lotz & Denis Gray (NSF I/UCRC Evaluator)

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Research Area 1 - Clinical Outcomes

1. Identifying Risk Factors for Pseudarthrosis

2. Implementation of a mobile application in the treatment of chronic nonspecific low back pain

3. Deep learning lesion mapping and expected patient outcomes from spinal radiographic imaging

4. The Fitbit Effect in Lumbar Spine Surgery, 1 to 2 year follow-up study

5. Development of a Total Joint Arthroplasty Registry at an Academic Tertiary Referral Center for the Study of Race and Socioeconomic-Based Outcome Disparities

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BREAK (snacks provided)

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Research Area 2 - Biomechanics

1. Incorporating Active Apex Correction alongside Guided Growth Technique: Avoiding Risky -Osteotomies and the Loss of Correction in Early Onset Scoliosis

2. Spino-pelvic Biomechanics for the Treatment of Spinal Disorders- A Finite Element Study

3. Development of a Protocol to Evaluate Growth Rods in a Missing Vertebra Model

4. Effect of Tapered Bone Cement Injection on the PJK in a Finite Element Model with Muscle Forces

5. Biomechanics of Lateral Inter Spinous Spacer and Lateral Cage for Spinal Fusion

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FDA/CDMI Update

Andrew Baumann, PhD - Division of Applied Mechanics, U.S. Food and Drug Administration

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LUNCH

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NSF I/UCRC Presentation

Andre W. Marshall, PhD - NSF I/UCRC Program Director

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Technology Presentations

• Latest on Imaging and Back Pain

      Aaron Fields, PhD, Assistant Professor, Department of Orthopaedic Surgery

• 3D printing yesterday, today, and tomorrow

      Alexis Dang, MD, Associate Professor, Department of Orthopaedic Surgery

BREAK (snacks provided)

Research Area 3 - Innovative Devices, Tools, or Assessment Techniques

1. Pedicle Screw Handling During Surgery Contribute to Bioburden and Potential Approaches to Reduce Rate of Infection in Patients– A Multi-Center Study

2. Static and dynamic changes in spinopelvic parameters and sagittal alignment

3. Development of a 3D printed scaffold for restoring muscle attachment in posterior spine surgery

4. Improved orthopedic pre-surgical planning using high-fidelity CT/MRI derived 3D Augmented Reality models

5. Sensorized SMART Spine Brace for Assessment and Tracking of Post-surgical Recovery

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BREAK (snacks provided)

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Research Area 4 - Other Topics

1. Magnetic Injectable Self-Setting Calcium Phosphate Cement (CPC) Compositions for Hyperthermia Treatment of Bone Tumors

2. Insights into Cartilage Tissue Property Changes in Osteoarthritis through Advanced Glycation End-Products

3. Feasibility and Biocompatibility of SLA 3D printed, nano beta-TCP scaffolds

4. Low-intensity Pulsed Ultrasound as a Novel Therapy for Disc Repair and Reduction of Disc Degeneration

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BREAK (snacks provided)

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Final 2017-2018 Project Presentations: UC San Francisco

1. High-throughput screening for osteocyte-mediated bone remodeling (OMBRE) regulatory compounds

2. Nerve/Bone Crosstalk: PEMF control of cAMP-sensitive TGFb signaling

3. Predictive modeling for clinical outcomes and cost-effectiveness of surgery for lumbar degenerative pathologies and spinal deformity

4. Mechanisms of post-discectomy vertebral endplate changes

5. Animal Model to Characterize Natural History of Intracept Basivertebral Nerve Ablation

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Review of Day 2 Activities and CDMI Organizational Meeting/Formative Discussion

Drs. Jeffrey Lotz & Denis Gray

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RECEPTION (hors d’oeuvres + drinks)