The Ohio State University hosts CDMI Spring Symposium
Researchers, clinicians, and high-level executives from top industrial and orthopaedic companies came together during April 11-12, 2019 to learn about the latest musculoskeletal innovations from CDMI's four different sites at UC San Francisco, University of Toledo, The Ohio State University, and Northeastern University. In this semi-annual event, the Center's Industry Advisory Board also determined the research roadmap for the next funding cycle and heard updates from our current projects.
CDMI Expands to The Ohio State University as Third NSF Musculoskeletal Site
SEPTEMBER 20, 2018
The Center for Disruptive Musculoskeletal Innovations (CDMI), a collaborative healthcare research center funded by the National Science Foundation (NSF) has added the expertise of The Ohio State University’s Spine Research Institute. CDMI is an NSF Industry/University Cooperative Research Center (I/UCRC) launched in 2014 by the University of California San Francisco and the University of Toledo. CDMI represents an exciting and novel integration of healthcare economics, biomedical science and clinical medicine. University faculty and industry partners are able to collaborate on novel technologies that will decrease healthcare costs and improve the management and life of patients with musculoskeletal disease. Read more here.
CDMI at NASS 2018, Los Angeles, California
WEDNESDAY, SEPT 26th
Abstract Presentations: Understanding Lumbar Stenosis/ Spondylolisthesis - Room 403A
12. A Preoperative Score for Predicting 30-Day Readmission after Elective 1-2 Level Posterior Lumbar Fusion
Deeptee Jain, MD; Paramjit Singh, MD, MA; Mayur Kardile,
MD; Sigurd H. Berven, MD
Innovative Technology Presentations - Room 404AB
Spinal Balance: Reducing Bacterial Dose During Instrumented Spine Surgery: A Clinical Study on a Novel and Effortless Method
Aakash Agarwal, PhD; Boren Lin, PhD; Neel Anand, MD; Jeffrey C. Wang, MD; Anand Agarwal, MD; Christian Schultz, MD, MBA; Hossein K. Elgafy, MD, FRCSC, FRCS; Vijay K. Goel, PhD; Steven R. Garfin, MD; Dennis P. McGowan, MD; Chris Karas, MD
Innovative Technology Presentations - Room 404AB
Medtronic: 3D-Printed Rough Titanium Implant for Intervertebral Body Fusion: An In Vitro Evaluation Using Osteoblast Precursor Cells
Ping Li, PhD; Jeremy Rawlinson, PhD; Cindy Ogden; William Armstrong; Brian Murrell; Virginia Richardson
Medtronic: Biological Response to Additive Titanium Implants in an Ovine Model
Jeremiah T. Easley, DVM; Jeremy Rawlinson, PhD; Christian M. Puttlitz, PhD; Howard B. Seim III, DVM; Kirk C. McGilvray, PhD
Surgical Innovation Lab Demonstrations - The Learning Place
Orange Lab: Relievant Medsystems
The Intracept® Procedure for the Relief of Chronic Low Back Pain
Speakers: Jeffrey Lotz, PhD; Jeffrey Fischgrund, MD; Ray Baker, MD; Alfred Rhyne, MD
THURSDAY, SEPT 27
Abstract Presentations: Lumbar Spine Surgery: What You Need to Know - Room 403A
111. Fibular Allograft as a Salvage Option in Revision Pedicle Screw Fixation
Hossein K. Elgafy, MD, FRCSC, FRCS; Nathaniel Lempert, MD; Jacob B. Stirton, MD; Peter W. Zak, MD
Section on Biologics and Basic Research Abstract Presentations - Room 404AB
128. Comparative Study of Cellular Bone Matrices for Posterolateral Spinal Fusion
Clifford Lin, MD; Paolo Antonio R. Punsalan, MD; Nianli Zhang, PhD; Jung U. Yoo, MD; Eric Semler, PhD; Erik I.Waldorff, PhD; James T. Ryaby, PhD; Brian Johnstone, PhD
Section on Biologics and Basic Research: Injectable Biologic Therapies for Intervertebral Disc - Room 404AB
What is Truth and What is Fiction: Current Evidence for Stem Cell Injections
Jeffrey Lotz, PhD
FRIDAY, SEPT 28th
NASS Recognition Awards Presentation - Concourse Hall 151
2018 Henry Farfan Award: Jeffrey C. Lotz, PhD
To recognize outstanding contributions in spine related basic science research.
Abstract Presentations: A New Look at Imaging - Room 403B
207. Noninvasive MR Spectroscopy (MRS) of Lumbar Discs Correlates with Surgery Outcomes in Discogenic Low Back Pain (DLBP) Patients
Matthew F. Gornet, MD; Jeffrey C. Lotz, PhD; Robert K. Eastlack, MD; James C. Peacock III, JD, BS; Francine W. Schranck, RN, BSN; John Claude; Anne G. Copay, PhD
Abstract Presentations: The Gravity of Obesity - Room 403B
229. Risk Factors for Readmission and Complications in Obese and Severely Obese Patients Undergoing Elective Posterior Lumbar Spine Fusion
Deeptee Jain, MD; Jeremy D. Shaw, MD; Vedat Deviren, MD; Alan Zhang, MD; Sigurd H. Berven, MD
P140. Registry Outcomes of Cement Augmentation for Osteoporotic Vertebral Compression Fractures
Neal H. Shonnard, MD; Sigurd H. Berven, MD; Paul A.
Anderson, MD; Douglas P. Beall, MD
Innovative Technology Posters
Technical Exhibition - Innovative Technology Posters are submitted and presented by exhibiting companies. Posters are available in the Technical Exhibition during all exhibit hours.
Board #2 Spinal Balance: Reducing Bacterial Dose During Instrumented Spine Surgery: A Clinical Study on a Novel and Effortless Method
Board #5 DePuy-Synthes: Mechanomyography (MMG) is Superior to EMG in Mapping and Locating Nerves at Risk During Spinal Surgery
Board #6 DePuy-Synthes: Comparative Ethnographic Study of the UNLEASH™ MIS TLIF Procedural Solution in a Cadaveric Lab
Board #7 Medtronic: Use of A Low-Thermal Injury Dissection Device Reduces Tissue Temperature Change in Anterior Lumbar Interbody Fusion Spine Surgery
Board #11 Medtronic: 3D-Printed Rough Titanium Implant for Intervertebral Body Fusion: An In Vitro Evaluation Using Osteoblast Precursor Cells
Board #12 Medtronic: Biological Response to Additive Titanium Implants in an Ovine Model
CDMI PIs at ISSLS 2018, Banff, Canada
Monday, May 10th, 14:00-17:00
SESSION 1: Novel Therapeutic Approaches and Preclinical Translation
Moderators: Lisbet Haglund, Ph.D.McGill University, Can & James Kang, M.D. – Harvard University, USA
Treating discogenic pain with intravertebral electrothermal nerve ablation
Jeffrey Lotz, Ph.D. – University of California San Francisco, USA
Tuesday, May 15th
SESSION #4: MRI Phenotypes
Chair: Dawn Elliott & Gwendolyn Sowa
Quantitative imaging of bone marrow composition reveals significant alterations in marrow fat content in patients with modic changes
A.J. Fields, A. Ballatori, M. Han, J.F. Bailey, A. Rochette, D. Jain, Z. McCormick, C. O'Neill, S. Deviren, R. Krug, J.C. Lotz, USA
SESSION #5: Low Back Pain
Chair: Mamoru Kawakami & Dilip Sengupta
Serum biomarkers for Modic changes among chronic low back pain patients
J. Karppinen, K. Koivisto, J. Ketola, M. Haapea, M. Paananen , K. Herzig, M. Alini, J. Lotz, S. Dudli, D. Samartzis, J. Risteli, M. Majuri, H. Alenius, E. Kyllönen, J. Järvinen, J. Niinimäki, S. Grad, Finland, Switzerland, USA, Swede
SYMPOSIUM #1 - Digital Health for Spine Providers
Chairs: Matthew Smuck and Markus Melloh
In-Clinic Diagnostic Motion Analysis - Jeffrey Lotz, PhD
Thursday, May 17th
SESSION #9 Biomechanics
Chairs: Grace O’Connell & Hans-Joachim Wilke
Altered multifidus muscle quality following long-duration spaceflight affects lumbar lordosis and compression on the intervertebral disc
J.F. Bailey, K.T. Khieu, R. Healey, C. ONeill, D. Coughlin, J. Sayson, D.G. Chang, A.R. Hargens, J.C. Lotz, USA
SESSION #10 Endplate
Chairs: John Costi & Dino Samartzis
Cartilage endplate damage strongly associates with chronic low back pain, independent of modic changes
A.J. Fields, A. Ballatori, M. Han, P.E. Larson, J.F. Bailey, A. Rochette, D. Jain, Z. McCormick, C. O'Neill, S. Deviren, R. Krug, J.C. Lotz, USA
Thursday, May 17th, continued
SESSION #15 Spinal Alignment
Chairs: Samuel Bederman & Kazuyuki Watanabe
Dynamic sagittal balance associates with patient-reported disability in adult spinal deformity population
J.F. Bailey, P.F. Curran, D. Beckerman, J.C. Lotz, S. Burch, USA
Friday, May 18th, Ivor Petrak Room - 07:45-08:45
SP #2F MUSCLE, DISC, LBP
Chairs: John Costi & Todd Alamin
SP 32 Douglas G Chang R.M. Healey, J.F. Bailey, J.V. Sayson, K. Khieu, S. Parazynski, J.C. Lotz, A.R. Hargens
Regional patterns of lumbar paraspinal muscle degeneration in astronauts after long-duration spaceflight on the international space station
SP 57 Conor ONeil S. Burch, M. Callahan
Population level analysis of health-related quality of life in patients with spinal disorders
GENERAL POSTER SESSION
Thursday, May 17th, 15:00-16:00
GP 33 John T Martin S.E. Gullbrand, A.J. Fields, D. Purmessur, A.D. Diwan, J.A. Hoyland, J.C. Iatridis
Publication trends in spine research: comparison of the Orthopaedic Research Society Spine Section and the International Society for the Study of the Lumbar Spine
GP130 John Ibrahim S. Lee, P. Singh, S. Burch, S. Berven
Appropriate use of surgery for adult spine deformity: a multidisciplinary perspective
GP 152 Sibel Demir H. Cil, Z.L. McCormick, S. Berven, J. Lotz
Type 1 Modic changes in degenerative disc disease are associated with increased fatty infiltration of the lumbar paraspinal muscles over time
GP 200 Sibel Demir H. Cil, Z.L. McCormick, J. Lotz, S. Berven
The association of type 1 Modic changes, paraspinal muscle atrophy, pain and function in individuals with lumbar disc herniation
GP 201 John Ibrahim D. Beckerman, A. Tenorio, L. Racine, S. Burch, S. Berven
Infection as an etiology for pseudarthrosis in multilevel spinal fusions
CDMI PIs at AAOS and ORS 2018
American Academy of Orthopaedic Surgeons (AAOS) Annual Meeting
Tuesday, March 6th, 7:00 AM - 6:00 PM, Academy Hall B
Classification: Adult Reconstruction Hip
SE05: The Consensus Statement of American Association of Hip and Knee Surgeons, American Academy of Orthopaedic Surgeons, Hip Society, Knee Society, and American Society of Regional Anesthesia on Tranexamic Acid in Total Joint Arthroplasty. Stefano Bini, MD
Classification: Adult Reconstruction Knee
SE18: Hypersensitivity Responses to Implants: Mechanisms, Diagnosis, Evaluation, and Management. Stefano Bini, MD
Thursday, March 8th, 7:00 AM - 6:00 PM, Academy Hall B
Classification: Adult Reconstruction Knee
P0675: Predictors of Clinically Meaningful Improvement in Patient Reported Outcomes Following Primary Total Knee Arthroplasty. Stefano Bini, MD
P0677 Risk-Adjusted Complication Rates Fail to Control for the Complexity of Total Hip and Knee Arthroplasty Patients in Academic Medical Centers. Stefano Bini, MD
Tuesday, March 6th, 10:30 AM - 12:30 PM, Theater A
Symposium: Innovation, Robotics, and Digital Solutions in Arthroplasty: Evolving Role in the Operating Room and Beyond!
New Technology is Cost Effective. Stefano Bini, MD
Wednesday, March 7th
8:00 - 10:00 AM, Theater A
Mind the Gap: Transition of the Adolescent to Adulthood. Sigurd Berven, MD
11:00 AM - 12:00 PM, Technology Theater Schedule – Booth 4569
The Way I See It…Leveraging Digital Technology: Managing Patients from Afar. Stefano Bini, MD
4:00 - 6:00 PM, Room 349
ICL #272: Evidence-Based Management of Spine Conditions in the Elite Athlete. Koichi Sairyo, MD
Thursday, March 8th, Room 245, Paper Presentation
2:42 - 2:48 PM
562 Risk Factors for Readmission in Obese and Severely Obese Patients Undergoing Elective Posterior Lumbar Spine Fusion. Sigurd Berven, MD
Saturday, March 10th, Room 271
3:13 PM - 3:21 PM
Risk Stratification-Expected and Observed Complications and Predictive Modeling. Sigurd Berven, MD
3:57 PM - 4:05 PM
Surgical Strategies to Optimize Efficiency and Outcomes. Shane Burch, MD
Orthopaedic Research Society (ORS) Annual Meeting
Friday, March 9th, 3:00 - 6:00 PM; PRE-ORS
ORS Spine Section Scientific Meeting. William Marras, PhD, CPE; Jeffrey Lotz, PhD.
Saturday, March 10th, 8:00 - 9:30 AM
SCIENTIFIC WORKSHOP: Outcome Measures in Orthopaedic Research of the Joints and Spine
Are Sensors the Holy Grail of PROs? What Digital Technology Will Mean for Quality Measures. Stefano Bini, MD
1:00-1:30 PM, Room Empire C&D
SPOTLIGHT SESSION 8, Bone Remodeling. Osteocyte Control of Bone Quality Through Perilacunar Remodeling. Tamara Alliston, PhD
2:45-2:50 PM SESSIONS, Room Empire C&D
SESSION 13 POSTER TEASERS, Paper No. 1654 Development and Validation of DNA Origami Biosensors to Study Osmotic Mechanotransduction in the Spine. William Marras, PhD, CPE
Sunday, March 11th, 5:30 - 5:40 PM, Room Celestin F&H
SESSION 28, Disc Imaging and Mechanics
Paper No. 0161 Associations Between Disc Biochemical Composition and Vertebral Body Fat Fraction Using Quantitative MRI. Jeffrey Lotz, PhD
Monday, March 12th, 4:06 PM, Room Celestin F-H
SESSION 24 NIRA - Spine, Tendon, and Ligament
Paper No. 0144 Detection of Internal Tissue Disruptions Within Injured Intervertebral Discs via Magnetic Resonance Elastography. William Marras, PhD, CPE
4:30 - 5:30 PM
ORS DEBATE: Osteoarthritis (OA) Is a Disease of Bone
Moderator: Tamara Alliston, PhD
Tuesday, March 13th, 10:15 - 10:25 AM, Room Empire A
SESSION 51 Cartilage: Osteoarthritis
Paper No. 0281 Blocking TGF-β1 With Oral Losartan Administration Improves Microfracture-Mediated Cartilage Repair. Tamara Alliston, PhD
Monday, March 12th, 8:00 AM - 5:30 PM, Elite Hall
POSTER SESSION 2, 3:15 PM - 4:15 PM, poster viewing and presenters
Poster No. 1689 Dynamic Sagittal Balance Associates With Patient Reported Disability in Adult Spinal Deformity Population. Jeffrey Lotz, PhD; Shane Burch, MD
CDMI makes big strides with another successful symposium
September 28-29th, 2017
The National Science Foundation’s Center for Disruptive Musculoskeletal Innovations (CDMI) held its fourth annual fall symposium at the UCSF Mission Bay campus on September 28-29, 2017. During the event, CDMI
Director (Jeffrey C. Lotz, PhD) presented a summary of the Center's 2016-17 accomplishments and the Center Industry Advisor Board (IAB)selected the 2017-18 project grant awardees. The finalists went through a six-month selection process beginning with 115 project ideas that were narrowed down to the final 21 through multiple IAB deliberations. Selected projects covered a range of topics, including wearable sensors to track surgical outcomes, implant surface modifications to prevent infection, implant biomechanics, and systems for high-throughput drug screening for
for bone healing.
More than 75 center members attended in person or via WebEx,
including industry members, FDA representatives, researchers, clinicians, and students from UC San Francisco, University of Toledo, Northeastern University, The Ohio State University, Technologico de Monterrey (Mexico), and Ulm University (Germany).
This year, the CDMI welcomed new affiliate sites at Northeastern University and The Ohio State University. “We are delighted to have two new affiliate sites join the CDMI and are looking forward to adding more sites and recruit even more industry partners during our renewal year, “ noted Dr. Lotz. “We are ready to take the CDMI to the next level via strategic growth that provides valued benefits for our industry partners.”
This year's guest speakers were CDMI/CERSI Engineering Intern Thomas Graf, who presented his findings from his summer internship at the FDA on a spinal implant computational model roadmap; and FDA Director Dr. Anton Dmitriev, who gave a preview of the upcoming Smart Sensor Public Workshop that will be held at FDA and co-sponsored by the CDMI. For the upcoming fifth year, the CDMI will hold its Spring Symposium at the University of Toledo.
Center celebrates third anniversary and builds membership base
April 5-6th, 2017
the CDMI 2017 Fall Symposium at UCSF in September. All participants are encouraged to provide feedback about their experience to help shape the September’s Fall Symposium.
“The CDMI Symposium afforded a great opportunity for both graduate and undergraduate students to not only present their research in a professional setting, but also to further their research through the feedback and insights given by experts in industry, faculty, and the eminent scholar guests,” said CDMI Co-Director Vijay Goel, PhD.
On April 5, 2017, the Center for Disruptive Musculoskeletal Innovations gathered for its semi-annual spring symposium at the University of Toledo in Toledo, Ohio. Over 100 researchers and industry representatives from UCSF, University of Toledo, Allegheny Singer Research Institute, The Ohio State University, and Wright University attended the two-day meeting. (Photo: Courtesy of the University of Toledo)
Beginning its fourth year, the Center for Disruptive Musculoskeletal Innovations (CDMI) held its Spring Symposium at the University of Toledo. With growing interest of expanding the CDMI to more universities, representatives from Allegheny Singer Research Institute, The Ohio State University, Northeastern University and Wright University also participated. This year's keynote speaker was NSF's Program Director of the Biomedical Engineering Program, Dr. Michele J. Grimm, who gave an insightful talk on navigating BME-related funding programs.
The 2016-17 CDMI grant awardees at the symposium presented their mid-year project updates to the Center’s Industry Advisor Board (IAB) members. All Center members voted on the 2017-18 Research Roadmap that will be used to attract the new 2017-18 cycle proposals. In the last two years, the IAB has reviewed over 80 proposals and have been enthusiastic of the projects' diversity. This year's
finalists will be selected during
An exciting addition during this past year was the recruitment of technology scouts that gave overviews of the cutting-edge technologies and studies in digital health (Britta Berg-Johansen, PhD Candidate, UC San Francisco) and biomaterials (Stephen Jaffee, Research Intern, Allegheny General Hospital). Matt Callahan (Analytics Program Manager at UCSF Department of Orthopaedic Surgery) also shared information on national, State, and UCSF patient databases that UCSF PIs have accessed for cost and clinical outcomes research. These reports were intended to be informational and to trigger PIs and the CDMI Industry Advisory Board (IAB) to stimulate potential CDMI projects.
Center's fiscal growth continues
"CDMI support was key for our early-stage project. Besides fostering interdisciplinary collaboration between labs, it provided us with opportunities for industry feedback and IP-related legal guidance. Simply put, the IUCRC-CDMI model allowed us to rapidly turn a new idea into data that support proof-of-concept for a novel back pain treatment,” said project PI Aaron Fields, PhD, Assistant Professor, Department of Orthopaedic Surgery, UCSF.
In addition, the CDMI has sustained its
The CDMI continues to gain momentum. At the close of its third year, it has leveraged the $40,000 per industry member fee by nearly $2,400,000 in cash support and more than $500,000 in capital and in-kind contributions. The CDMI also continues to expand its collaborations. “We are pleased to have Dr. Sean Tunis, Founder and CEO of the Center for Medical Technology Policy, join the CDMI as Reimbursement Liaison,” notes Jeffrey Lotz, PhD, CDMI Center Director.
“With his help, the CDMI is working towards developing projects with clinical cost analysis in mind by attracting payors to join the Center.”
More than 30 abstracts and manuscripts have been submitted by the CDMI awardees and may be found online. A second team of CDMI collaborators have filed a patent for the “Enhancing Disc Endplate Permeability” project which was started as a collaboration between UCSF researchers Aaron Fields, PhD; Francis Szoka, PhD; and Jeffrey Lotz, PhD.
collaboration with the FDA as it is gearing up to work on a new project to gather biomechanical testing requirements for intervertebral implants, as well as determine a roadmap for replacing these tests with computational models.
CDMI Fall Symposium -- A Success!
September 29th-30th, 2016
The National Science Foundation’s Center for Disruptive Musculoskeletal Innovations (CDMI) held its third annual fall symposium at the UCSF Mission Bay campus during September 29-30, 2016. The event, which was attended by researchers, clinicians and industry members, presented the center’s summary of its second year’s accomplishments as well as selecting the 2016-2017 project grant awardees. More than 75 center members attended, in addition to being broadcast via webcast to remote CDMI members.
“We were thrilled by the turnout,“ noted Jeffrey C. Lotz, PhD, CDMI Director. “We were able to review over 20 proposals on highly-innovative subjects that will change the way we provide solutions to musculoskeletal problems in the future.”
During the 2016 Fall CDMI Symposium, attendees listened to individual project proposals and the CDMI Industry Advisory Board voted on which would be funded; 12 proposals received up to $40,000 one-year grants.
Dr. Stefano Bini, MD, was one of 21 presenters, who identified a research project that focused on the center’s mission of addressing unmet market needs in musculoskeletal research. Dr. Bini’s project focuses on digital health, and was one of eight recipients of a CDMI grant. (Photo: UCSF)
The Center for Disruptive Musculoskeletal Innovations (CDMI) – a collaboration funded by the National Science Foundation between researchers at the University of California, San Francisco and the University of Toledo – completed its first year with great success.
“The CDMI has gained great momentum since its launch in 2014.” Jeffrey Lotz, PhD, the Center’s Director, said. “At the close of our first year, we have been able to leverage the $40,000 per industry member fee by almost $2,400,000 in cash support and more than $500,000 in capital and in-kind contributions. We are proud of these accomplishments and especially the partnership that we have been able to form with our Industry Board Members and other entities like the FDA. We are looking forward to an even brighter third year.”
So far more than 15 abstracts have been submitted by the CDMI awardees, many of which are under publication. In addition, a team of CDMI collaborators have filed a patent that came out of a project entitled Quantitative Tool Using Impedance Spectroscopy to Monitor Fracture Healing. The project started as a joint collaboration between a UCSF clinician (Meir Marmor, MD) and research faculty members from UCSF (Chelsea Bahney, PhDand Safa Herfat, PhD) and UC Berkeley (Michel Maharbiz, PhD).
“This has been a very exciting project to work on and is a great example of the power of cross-disciplinary team science. The project stemmed from a clinical need for better ways to detect progression of fracture healing. By establishing a collaboration between Electrical Engineering and Computer Science at UC Berkeley, and a team of clinicians, bioengineers, and translational science faculty in the UCSF Orthopaedic Trauma Institute, we have coalesced the expertise necessary to develop and test a novel impedance spectroscopy device,” said Dr. Bahney, UCSF Assistant Adjunct Professor and a lead researcher on the project.
“This project has been driven by a very talented and motivated PhD candidate, Monica Lin. The award has provided her with the unique benefit of having industry advisors in addition to traditional academic advisors. CDMI is ideally positioned to help catalyze translation of new musculoskeletal technologies. We are very thankful for the seed-funding that has given our team the opportunity to explore an otherwise unfunded project that has significant potential for clinical impact,” Dr. Bahney added.
Center Unveils Several Successes in First Year
We are pleased to announce that this spring Dr. Anton Dmitriev (left) officially became a US Food and Drug Administration (FDA) Liaison to the CDMI. In such capacity, Dr. Dmitriev will present and receive information and views on behalf of the FDA. This was made possible, in part, by the FDA’s involvement in the UCSF-Stanford Center of Excellence in Regulatory Science and Innovation (CERSI) – a collaboration amongst scientists at UC San Francisco, Stanford University, and the FDA to support collaborative projects in regulatory science. Via an FDA-funded proposal thru CERSI, the CDMI has sent a UCSF medical student (David Sing, right) on a 6-month in-residence internship at the FDA, where he is collaborating with FDA staff to analyze 510k submission data for his study “Mechanical Testing Performance in Cervical Interbody Fusion Devices.” We are looking forward to his presentation update during the Fall 2015 CDMI Symposium.