CDMI Fall 2018 Symposium

September 13-14, 2018
UC San Francisco
Mission Bay Campus
 
 
This event is open to ALL MUSCULOSKELETAL industry representatives and university musculoskeletal researchers and clinicians.

Day 1 - Thursday September 13, 2018

Fisher Banquet Room West

 

7:30 am                  Registration

7:30 - 8:00 am        NETWORKING (BREAKFAST provided)

8:00 - 8:25 am        Welcome Remarks, Introductions & CDMI Update

Drs. Jeffrey Lotz & Vijay Goel – CDMI Site Directors

8:25 - 8:40 am        Introduction to Presentations

Drs. Jeffrey Lotz & Denis Gray (NSF I/UCRC Evaluator)

8:40 - 9:50 am       Research Area 1 - Clinical Outcomes

  • Determine the effect of reconstruction of the paraspinal musculature

  • Predictive modeling for clinical outcomes and cost-effectiveness of surgery for lumbar degenerative pathologies and spinal deformity

  • Development and validation of a classification for degenerative spondylolisthesis

  • Functional test of postural stability

  • Kinematics of recovery

  • A validation study using gait analysis to test the accuracy of wearable sensor data in postsurgical patients

9:50 - 10:00 am      BREAK (snacks provided)

10:00 - 10:55 am    Research Area 2 - Spine: Innovative Devices or

Surgical Techniques

  • Biomechanics of PJK with tapered cement injections in UV levels using PMMA and Ca-P

  • Design, development and evaluation of hybrid interspinous fusion device for lateral approach

  • Design, development and evaluation of an expandable interbody fusion device deployed via an endoscopic approach

  • Development of an innovative posterior pedicle-based screw stabilization for multilevel semi-dynamic stabilization

  • Biomechanical evaluation of the newly developed decompression surgery: Transforaminal ventral facetectomy

10:55 - 11:10 am    CDMI/CERSI/FDA Spinal Implant

Computational Model Roadmap

                               Thomas Graf, M.S. – CDMI/CERSI Engineering Intern

11:10 - 11:20 am    FDA Smart Sensor Public Workshop

Dr. Anton Dmitriev, FDA Director, Division of Applied Mechanics

11:20 - 11:35 am   The Ohio State University Planning Meeting Update

Dr. William Marras, Site Director, Professor, Executive

Director & Scientific Director of the Spine Research

Institute, The Ohio State University

11:35 - 12:45 pm    LUNCH

12:45 - 1:30 pm      Research Area 3 -

Innovative Devices/Tools/Equipment or Surgical Technique Evaluation

  • Onsite 3DPrinting of Precision Anatomic Models (PAMs) to improve surgical planning and education in Orthopaedics

  • A new fracture plate for long bone fracture reductions

  • Alignment of the lower limb following talotarsal stabilization using the titanium tent - clinical study

  • Transporter table system

 

1:30 - 1:40 pm        BREAK (snacks provided)

 

1:40 - 2:25 pm        Research Area 4 - Biomaterials

  • Development of hard antibacterial (TiN/Ag) coatings on orthopedic instruments fabricated from Ti-alloys

  • An injectable monetite based bone graft substitute with real-time formation of macropores

  • Creating biologically active surfaces that reduce infection: A combination of modeling and experiments

  • Self-assembled chemistries for disruptive musculoskeletal innovations

2:25 - 3:10 pm        Research Area 5 - Basic Science

  • Acceleration of explanatory mechanism discovery in the fracture healing process using artificial intelligence

  • High-throughput screening for osteocyte-mediated bone remodeling (OMBRE) regulatory compounds

  • Nerve/Bone crosstalk: PEMF control of cAMP-sensitive TGFb signaling

3:10 - 3:20 pm       BREAK (snacks provided)

3:20 - 4:00 pm       Final Project Presentation 2016-17

UC San Francisco

  • Wearable activity sensors and patient reports outcomes in total hip arthroplasty: a nested RCT

  • Analysis of the cause of pseudarthrosis in multilevel spinal fusions

  • Smart implant to detect fracture healing

 

4:00 - 4:20 pm       Review of Day 2 Activities and CDMI Organizational    

Meeting/Formative Discussion

Drs. Jeffrey Lotz & Denis Gray

4:20 - 6:00 pm        RECEPTION (hors d’oeuvres + drinks), Fisher Atrium

Day 2 - Friday September 14, 2018

Mission Hall

Global Health and Clinical Sciences Building, Room 2103

 

7:00 - 7:30 am        NETWORKING (breakfast provided)

7:30 - 9:00 am        LIFE FORM Review and Discussion of 

2017-18 Projects with Faculty

 

9:00 - 9:10 am        BREAK (snacks provided)

9:10 - 10:30 am       IAB Meeting – Voting Session

 (IAB Members and NSF only)

 

10:30 - 10:40 am     BREAK (snacks provided)

10:40 - 11:00 am     Discussion:

  • IAB Report Out

  • Action Items

  • Plans for Spring Symposium 2018 at the University of Toledo

11:00 - 11:40 am   Final Project Presentations from 2016-17

University of Toledo – part I

  • Development of juvenile FE models of the scoliotic spines to understand the clinically relevant failure mechanism of growth rods and clinical correlation

  • How lumbar disc geometries affect the risk for rod fracture in patients undergoing adult spine deformity surgery

  • Biomechanics of topping off the fused segment

11:40 - 12:30 pm   LUNCH in parallel with presentations

11:50 - 12:30 pm   Final Project Presentations from 2016-17

University of Toledo – part II

  • Immune responses associated with development of spine deformity

  • Vertebral cage subsidence is a function of the cage design, besides the variation in vertebral bone mineral density

  • Lumbar-sacral destruction and other SIJ fixation biomechanics –  Continuation of Phase I

 

12:30 - 12:35 pm   Closing Remarks

Dr. Jeffrey Lotz

Come together with researchers, clinicians, and high level executives from top orthopaedic companies to learn about the latest musculoskeletal innovations from 4 different campuses (UC San Francisco, University of Toledo, The Ohio State University, and Northeastern University). In this semi-annual event, the center's Industry Advisory Board also will choose which projects to fund and will hear about the center's results from collaborative initiatives with the FDA and previously funded university projects.

© 2019 Center for Disruptive Musculoskeletal Innovations