​

​

​

Day 1 - Thursday September 13, 2018

Fisher Banquet Room West

 

7:30 am                  Registration

​

7:30 - 8:00 am        NETWORKING (BREAKFAST provided)

​

8:00 - 8:25 am        Welcome Remarks, Introductions & CDMI Update

Drs. Jeffrey Lotz & Vijay Goel – CDMI Site Directors

​

8:25 - 8:40 am        Introduction to Presentations

Drs. Jeffrey Lotz & Denis Gray (NSF I/UCRC Evaluator)

​

8:40 - 9:50 am       Research Area 1 - Clinical Outcomes

• Determine the effect of reconstruction of the paraspinal musculature

• Predictive modeling for clinical outcomes and cost-effectiveness of surgery for lumbar degenerative pathologies and spinal deformity

• Development and validation of a classification for degenerative spondylolisthesis

• Functional test of postural stability

• Kinematics of recovery

• A validation study using gait analysis to test the accuracy of wearable sensor data in postsurgical patients

​

9:50 - 10:00 am      BREAK (snacks provided)

​

10:00 - 10:55 am    Research Area 2 - Spine: Innovative Devices or

Surgical Techniques

• Biomechanics of PJK with tapered cement injections in UV levels using PMMA and Ca-P

• Design, development and evaluation of hybrid interspinous fusion device for lateral approach

• Design, development and evaluation of an expandable interbody fusion device deployed via an endoscopic approach

• Development of an innovative posterior pedicle-based screw stabilization for multilevel semi-dynamic stabilization

• Biomechanical evaluation of the newly developed decompression surgery: Transforaminal ventral facetectomy

​

10:55 - 11:10 am    CDMI/CERSI/FDA Spinal Implant

Computational Model Roadmap

                               Thomas Graf, M.S. – CDMI/CERSI Engineering Intern

​

11:10 - 11:20 am    FDA Smart Sensor Public Workshop

Dr. Anton Dmitriev, FDA Director, Division of Applied Mechanics

​

11:20 - 11:35 am   The Ohio State University Planning Meeting Update

Dr. William Marras, Site Director, Professor, Executive

Director & Scientific Director of the Spine Research

Institute, The Ohio State University

​

11:35 - 12:45 pm    LUNCH

​

12:45 - 1:30 pm      Research Area 3 -

Innovative Devices/Tools/Equipment or Surgical Technique Evaluation

• Onsite 3DPrinting of Precision Anatomic Models (PAMs) to improve surgical planning and education in Orthopaedics

• A new fracture plate for long bone fracture reductions

• Alignment of the lower limb following talotarsal stabilization using the titanium tent - clinical study

• Transporter table system

 

1:30 - 1:40 pm        BREAK (snacks provided)

 

1:40 - 2:25 pm        Research Area 4 - Biomaterials

• Development of hard antibacterial (TiN/Ag) coatings on orthopedic instruments fabricated from Ti-alloys

• An injectable monetite based bone graft substitute with real-time formation of macropores

• Creating biologically active surfaces that reduce infection: A combination of modeling and experiments

• Self-assembled chemistries for disruptive musculoskeletal innovations

​

2:25 - 3:10 pm        Research Area 5 - Basic Science

• Acceleration of explanatory mechanism discovery in the fracture healing process using artificial intelligence

• High-throughput screening for osteocyte-mediated bone remodeling (OMBRE) regulatory compounds

• Nerve/Bone crosstalk: PEMF control of cAMP-sensitive TGFb signaling

​

3:10 - 3:20 pm       BREAK (snacks provided)

​

3:20 - 4:00 pm       Final Project Presentation 2016-17

UC San Francisco

• Wearable activity sensors and patient reports outcomes in total hip arthroplasty: a nested RCT

• Analysis of the cause of pseudarthrosis in multilevel spinal fusions

• Smart implant to detect fracture healing

 

4:00 - 4:20 pm       Review of Day 2 Activities and CDMI Organizational    

Meeting/Formative Discussion

Drs. Jeffrey Lotz & Denis Gray

​

4:20 - 6:00 pm        RECEPTION (hors d’oeuvres + drinks), Fisher Atrium

​

​